Lindera cyclopentenedione intermediates from the roots of Lindera aggregata
نویسندگان
چکیده
منابع مشابه
A pair of windmill-shaped enantiomers from Lindera aggregata with activity toward improvement of insulin sensitivity.
(+)-Linderaspirone A and (-)-linderaspirone A, a pair of natural windmill-shaped enantiomers, were isolated from the traditional Chinese medicine plant Lindera aggregate by HPLC using a chiral column, achieving over 98% ee. Their structures and absolute configurations were determined on the basis of extensive analysis of NMR spectra, crystal X-ray diffraction, and calculation of the optical rot...
متن کاملSecoaggregatalactone-A from Lindera aggregata induces apoptosis in human hepatoma hep G2 cells.
A new secobutanolide, secoaggregatalactone A ( 1) was isolated from the leaves of Lindera aggregata. Results obtained from the cytotoxicity assay revealed that secoaggregatalactone A exhibited a noticeable cytotoxicity (EC (50) = 6.61 microg/mL; 22.1 microM) against the human hepatoma cell line (Hep G2 cell line). According to morphological observations, flow cytometric analysis, and DNA fragme...
متن کاملNew cytotoxic butanolides from Lindera obtusiloba BLUME.
Three new butanolides, 2-(1-methoxy-11-dodecenyl)-penta-2,4-dien-4-olide (1), (2Z,3S,4S)-2-(11-dodecenylidene)-3-hydroxy-4-methylbutano lide (2) and (2E,3R,4R)-2-(11-dodecenylidene)-3-hydroxy-4-methoxy-4-methylbu tanolide (3), were isolated from the stems of Lindera obtusiloba BLUME. Their chemical structures were assigned by spectroscopic evidence. They exhibited cytotoxicity against cultured ...
متن کاملbrotic (+)-Episesamin Isolated from Lindera obtusiloba BLUME
In traditional Korean medicine, an aqueous extract of the plant Lindera obtusiloba has been used for centuries to treat infl ammation, improve blood circulation, and prevent liver damage (Yook, 1989). Recently, we demonstrated antifi brotic, antioxidative, anti-infl ammatory, and antiadipogenic activity of this extract (Rühl et al., 2009; Freise et al., 2009). Freise et al. (2011) documented th...
متن کاملBioactive lignan constituents from the twigs of Lindera glauca.
A bioassay-guided fractionation and chemical investigation of the MeOH extract from the twigs of Lindera glauca (SIEB. et ZUCC.) BLUME resulted in the isolation and identification of six lignans (1-6) including three new lignan derivatives, named linderuca A (1), B (2), and C (3). The structures of the new compounds (1-3) were determined on the basis of spectroscopic analyses, including two dim...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: RSC Advances
سال: 2018
ISSN: 2046-2069
DOI: 10.1039/c8ra03094d